E-ISSN 2583-7761
 

Original Research

Online Publishing Date:
17 / 08 / 2023

 


Detection Of Panton–Valentine Leukocidin Gene In Methicillin Resistance Staphylococcus Aureus: Clinical And Epidemiological Aspects

Sneha mohan, Sneha mohan, Tarana Sarwat, satendra pal singh, Dalip Kakru.


Abstract
Introduction: The role of PVL in the disease process and severity of S.aureus till now is a debate matter. The data provide substantial evidence that the high virulence potential of CA-MRSA isolates is associated with the expression of PVL. PVL genes carried by HA-MRSA strains have also been recently described in cutaneous and invasive infections. Epidemiology of MRSA strains is constantly changing and is known to vary between hospitals. This study aimed to analyze the prevalence of PVL in MRSA isolates from patients using multiplex PCR. Material and Methods: Staphylococcus aureus were isolated from various clinical samples received in Bacteriology Laboratory using standard protocol. Antibiotic susceptibility testing was performed by Kirby – Bauer disc diffusion method. Detection of PVL genes by multiplex PCR.Results: The highest prevalence of MRSA PVL positive isolates was from pus sample (74.5%) followed by blood (16.3%). The results of antimicrobial susceptibility testing revealed almost similar pattern of antibiotics resistance among PVL negative MRSA isolates as compared to PVL positive MRSA isolates. Conclusion: The detection of PVL-producing MRSA will help us in framing and planning the infection control measures against the MRSA infections.

Key words: Methicillin Resistance Staphylococcus Aureus, PVL gene, Multiplex PCR


 
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How to Cite this Article
Pubmed Style

mohan S, mohan S, Sarwat T, singh sp, Kakru D. Detection Of Panton–Valentine Leukocidin Gene In Methicillin Resistance Staphylococcus Aureus: Clinical And Epidemiological Aspects. A-JMRHS . 2023; 1(2): 37-41. doi:10.5455/AJMRHS.1107202300010


Web Style

mohan S, mohan S, Sarwat T, singh sp, Kakru D. Detection Of Panton–Valentine Leukocidin Gene In Methicillin Resistance Staphylococcus Aureus: Clinical And Epidemiological Aspects. https://www.ajmrhs.com/?mno=159766 [Access: March 14, 2024]. doi:10.5455/AJMRHS.1107202300010


AMA (American Medical Association) Style

mohan S, mohan S, Sarwat T, singh sp, Kakru D. Detection Of Panton–Valentine Leukocidin Gene In Methicillin Resistance Staphylococcus Aureus: Clinical And Epidemiological Aspects. A-JMRHS . 2023; 1(2): 37-41. doi:10.5455/AJMRHS.1107202300010



Vancouver/ICMJE Style

mohan S, mohan S, Sarwat T, singh sp, Kakru D. Detection Of Panton–Valentine Leukocidin Gene In Methicillin Resistance Staphylococcus Aureus: Clinical And Epidemiological Aspects. A-JMRHS . (2023), [cited March 14, 2024]; 1(2): 37-41. doi:10.5455/AJMRHS.1107202300010



Harvard Style

mohan, S., mohan, . S., Sarwat, . T., singh, . s. p. & Kakru, . D. (2023) Detection Of Panton–Valentine Leukocidin Gene In Methicillin Resistance Staphylococcus Aureus: Clinical And Epidemiological Aspects. A-JMRHS , 1 (2), 37-41. doi:10.5455/AJMRHS.1107202300010



Turabian Style

mohan, Sneha, Sneha mohan, Tarana Sarwat, satendra pal singh, and Dalip Kakru. 2023. Detection Of Panton–Valentine Leukocidin Gene In Methicillin Resistance Staphylococcus Aureus: Clinical And Epidemiological Aspects. Asian Journal of Medical Research & Health Sciences (A-JMRHS), 1 (2), 37-41. doi:10.5455/AJMRHS.1107202300010



Chicago Style

mohan, Sneha, Sneha mohan, Tarana Sarwat, satendra pal singh, and Dalip Kakru. "Detection Of Panton–Valentine Leukocidin Gene In Methicillin Resistance Staphylococcus Aureus: Clinical And Epidemiological Aspects." Asian Journal of Medical Research & Health Sciences (A-JMRHS) 1 (2023), 37-41. doi:10.5455/AJMRHS.1107202300010



MLA (The Modern Language Association) Style

mohan, Sneha, Sneha mohan, Tarana Sarwat, satendra pal singh, and Dalip Kakru. "Detection Of Panton–Valentine Leukocidin Gene In Methicillin Resistance Staphylococcus Aureus: Clinical And Epidemiological Aspects." Asian Journal of Medical Research & Health Sciences (A-JMRHS) 1.2 (2023), 37-41. Print. doi:10.5455/AJMRHS.1107202300010



APA (American Psychological Association) Style

mohan, S., mohan, . S., Sarwat, . T., singh, . s. p. & Kakru, . D. (2023) Detection Of Panton–Valentine Leukocidin Gene In Methicillin Resistance Staphylococcus Aureus: Clinical And Epidemiological Aspects. Asian Journal of Medical Research & Health Sciences (A-JMRHS), 1 (2), 37-41. doi:10.5455/AJMRHS.1107202300010